COVID-19 cases rise as new JN.1 subvariants spread across India

India is witnessing a renewed rise in COVID-19 cases, driven by the emergence and spread of new subvariants of the JN.1 strain. According to the Ministry of Health and Family Welfare, as of May 26, 2025, there are 1,009 active cases reported nationwide, with Kerala and Maharashtra recording the highest numbers. Experts caution that while symptoms remain largely mild, the heightened transmissibility and partial immune evasion of these subvariants warrant continued vigilance.

COVID-19 cases rise steadily across the country

The resurgence of COVID-19 infections in India is marked by a gradual but steady increase, with no major outbreaks or health system strain reported so far. The new surge is attributed primarily to the subvariants NB.1, NB.1.8.1, and LF.7, which belong to the JN.1 lineage and have been detected in several states including Kerala, Maharashtra, Tamil Nadu, and Delhi.

Kerala and Maharashtra report highest active COVID cases

Kerala currently leads with 430 active cases, followed by Maharashtra with 209, accounting for the majority of infections reported at present. Health officials are closely monitoring the situation to prevent further escalation, especially in urban clusters and vulnerable populations.

COVID subvariants show increased transmissibility and immune evasion

Virologists highlight that these subvariants possess enhanced transmissibility and demonstrate a degree of immune escape, increasing the risk of reinfections, even among vaccinated individuals or those previously infected.

Symptoms predominantly mild; vaccines continue to offer protection

To date, the majority of infections caused by these subvariants have presented with mild symptoms such as fatigue, sore throat, and low-grade fever. Importantly, current COVID-19 vaccines remain effective in preventing severe illness and hospitalisation related to these variants.

Authorities urge continued caution and adherence to preventive measures

Public health authorities emphasize that despite the absence of new restrictions, precautionary measures should be maintained. Individuals are advised to wear masks in crowded or enclosed spaces, seek testing if symptomatic, ensure booster doses are up to date, and sustain overall health to support immune resilience.

Early intervention critical to mitigate potential surge

While the current increase in cases remains contained, experts caution that without appropriate vigilance and timely action, the spread could accelerate. The government and health experts stress that proactive measures now are essential to avert a larger wave and associated health system impact in the near future.

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